† Based on internal sales data from FY01-FY23. November 2023.
‡ Compared to conventional methods/electrosurgery
§ 22 out of 23 surgeons surveyed agreed
Ω after 5 activations
†† As compared to conventional sutures.
‡‡ Animal data may not correlate with human clinical outcomes.
ΩΩ Compared to conventional electrocautery technique (5.9 vs 9.6 days, p<0.001).
1. Advanced Energy Procedures Claim_US161132(4) vCertification 1.1_10.24.19
2. Advanced Energy Historical Sales Data_FY20 Sept.
3. Ikeda N, Akahori T, Yokotani T, Fujii T, Sho M. Total Sealing Technique (TST) with a bipolar vessel sealing system reduces lymphorrhea and seroma formation for axillary lymph node dissection in primary breast cancer. Surg Open Sci. 2024; 19:1-7.
4. Ikeda, N.; Nagata, T.; Umemura, T.; Watanabe, M. Total Sealing Technique: A Preliminary Study on a Novel Surgical Approach That Significantly Reduces the Incidence of Upper Extremity Lymphedema Following Axillary Dissection in Patients with Breast Cancer. Cancers 2025, 17, 1285.
5. RE00114823_A RPT Surgeon Validation of LigaSure™ Exact LF2019
6. RE00107711_Harmonic Focus vs LigaSure Exact LF2019
7. R000153866_A RPT_Exact_Comp_Acute
8. Lee JS, Kim DG, Lee JW, et al. Usefulness of the LigaSure small jaw sealing device for breast reconstruction with a latissimus dorsi flap. J Plast Surg Hand Surg. May 2019:1–6.
9. Chang YW, Kim HS, Jung SP, et al. Comparison of skinsparing mastectomy using LigaSure Small Jaw andelectrocautery. World J Surg Oncol. 2017;15(1):129.
10. Seki T, Hayashida T, Takahashi M, Jinno H, Kitagawa Y. A randomized controlled study comparing a vesselsealing system with the conventional technique in axillary lymph node dissection for primary breast cancer.
Springerplus. 2016;5(1):1004.
11. Inoue Y, Yamashita N, Ueo H, et al. The Clinical Usefulness of the LigaSure Small Jaw in Axillary LymphNode Dissection in Patients with Breast Cancer. Anticancer Res. 2018;38(4):2359–2362.
12. Zaruby J, Gingras K, Taylor J, Maul D. An in vivo comparison of barbed suture devices and conventional monofilament sutures for cosmetic skin closure: biomechanical wound strength and histology. Aesthet Surg J. 2011;31(2):232-40.
©2025 Medtronic. All rights reserved, Medtronic. Medtronic logo and Engineering the extraordinary are trademarks of Medtronic. All other brands are trademarks of a Medtronic company. 09/2025 - US-SE-2200214